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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/11829

Title: Social Contact Patterns in Vietnam and Implications for the Control of Infectious Diseases
Authors: Horby, Peter
Pham Quang Thai
HENS, Niel
Nguyen Thi Thu Yen
Le Quynh Mai
Dang Dinh Thoang
Nguyen Manh Linh
Nguyen Thu Huong
Alexander, Neal
Edmunds, W. John
Tran Nhu Duong
Fox, Annette
Nguyen Tran Hien
Issue Date: 2011
Citation: PLOS ONE, 6 (2)
Abstract: Background: The spread of infectious diseases from person to person is determined by the frequency and nature of contacts between infected and susceptible members of the population. Although there is a long history of using mathematical models to understand these transmission dynamics, there are still remarkably little empirical data on contact behaviors with which to parameterize these models. Even starker is the almost complete absence of data from developing countries. We sought to address this knowledge gap by conducting a household based social contact diary in rural Vietnam. Methods and Findings: A diary based survey of social contact patterns was conducted in a household-structured community cohort in North Vietnam in 2007. We used generalized estimating equations to model the number of contacts while taking into account the household sampling design, and used weighting to balance the household size and age distribution towards the Vietnamese population. We recorded 6675 contacts from 865 participants in 264 different households and found that mixing patterns were assortative by age but were more homogenous than observed in a recent European study. We also observed that physical contacts were more concentrated in the home setting in Vietnam than in Europe but the overall level of physical contact was lower. A model of individual versus household vaccination strategies revealed no difference between strategies in the impact on R-0. Conclusions and Significance: This work is the first to estimate contact patterns relevant to the spread of infections transmitted from person to person by non-sexual routes in a developing country setting. The results show interesting similarities and differences from European data and demonstrate the importance of context specific data.
Notes: [Horby, Peter; Fox, Annette] Oxford Univ Clin Res Unit, Hanoi, Vietnam. [Horby, Peter; Fox, Annette] Univ Oxford, Nuffield Dept Clin Med, Ctr Trop Med, Oxford, England. [Pham Quang Thai; Nguyen Thi Thu Yen; Le Quynh Mai; Nguyen Manh Linh; Nguyen Thu Huong; Tran Nhu Duong; Nguyen Tran Hien] Natl Inst Hyg & Epidemiol, Hanoi, Vietnam. [Hens, Niel] Hasselt Univ, Diepenbeek, Belgium. [Hens, Niel] Univ Antwerp, Ctr Hlth Econ Res & Modeling Infect Dis, Vaccine & Infect Dis Inst, B-2020 Antwerp, Belgium. [Dang Dinh Thoang] Ha Nam Ctr Prevent Med, Ha Nam, Vietnam. [Alexander, Neal; Edmunds, W. John] London Sch Hyg & Epidemiol, London, England. peter.horby@gmail.com
URI: http://hdl.handle.net/1942/11829
DOI: 10.1371/journal.pone.0016965
ISI #: 000287367600026
ISSN: 1932-6203
Category: A1
Type: Journal Contribution
Validation: ecoom, 2012
Appears in Collections: Research publications

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