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|Title: ||CALCIUM AND VITAMIN D INTAKE AND THE NEED OF SUPPLEMENTS IN PATIENTS OLDER THAN 50 YEARS AT THE TIME OF FRACTURE|
|Authors: ||GEUSENS, Piet|
Van den Bergh, J.
|Issue Date: ||2010|
|Publisher: ||SPRINGER LONDON LTD|
|Citation: ||OSTEOPOROSIS INTERNATIONAL, 21. p. 190-191|
|Abstract: ||Aims: Adequate calcium and vitamin D intake is advocated in guidelines of osteoporosis and was calculated in patients at the time they presented with a fracture. Methods: Of 902 consecutive fracture patients, 502 were available for evaluation of calcium intake (by questionnaire) and serum 25 (OH)D. We calculated the percentage of patients who needed ³500mg/d of calcium to achieve ³1000 mg/d and who needed ³800
IU/d of vitamin D to achieve ³50 nmol/l. Results: Mean calcium intake was 839 mg/d (range 250-2050
mg) and mean 25(OH)D 43 nmol/l (range <10 to 130 nmol/l).
To achieve 1000 mg/d of calcium, 12% needed 1000 mg/d and
56% needed 500 mg/d, and to achieve 1200 mg/d, 32% and 61%,
respectively, without surpassing 1500 mg/d. Systematic supplements
of 500 mg/d would achieve 1000 mg/d in 88% and of 1000
mg/d in all, and increased the intake to >1500 mg/d in 30% of
patients with 500 mg/d and in 85% with 1000 mg/d. To achieve 50
nmol/l of 25(OH)D, 40% needed 800 IU/d vitamin D, 26% needed
higher doses, and, to achieve 75 nmol/l, 9% needed 2400 IU/d.
Systematic supplements of 800 IU/d would achieve 50 nmol/l in
75% of patients and 2000 IU/d in 91%. None of the these individualized or systematic doses of vitamin D supplements would bring 25(OH)D above the toxic level. Conclusions: Baseline values and future need of adequate calcium and vitamin D intake vary between fracture patients. Supplements need to be titrated accordin to the desirable need and safety limits.|
|Notes: ||[Geusens, P.; van den Bergh, J.] MUMC UH, Maastricht, Netherlands. [Geusens, P.] Univ Hasselt, Hasselt, Belgium.|
|ISI #: ||000277299400412|
|Type: ||Journal Contribution|
|Appears in Collections: ||Research publications|
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