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Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/10997

Title: Rasch-built myotonic dystrophy type 1 activity and participation scale (DM1-Activ)
Authors: Hermans, Mieke C. E.
Faber, Catharina G.
de Die-Smulders, Christine E. M.
Merkies, Ingemar S. J.
Issue Date: 2010
Citation: NEUROMUSCULAR DISORDERS, 20 (5). p. 310-318
Abstract: We describe the development of an outcome measure of activity and participation for patients with myotonic dystrophy type 1 using the Rasch measurement model. A 49-item questionnaire was completed by 163 DM1 patients. Data were subsequently analyzed with Rasch software to design the item set to fit model expectations. Through systematic investigation of response category ordering, model fit, item bias, and local response dependency, we succeeded in constructing a 20-item unidimensional scale of activity and participation (DM1-Activ). High internal consistency (PSI = 0.95) and good test-retest reliability values of item difficulty hierarchy and patient location were demonstrated. Patient measures had acceptable correlations with MRC sum scores and MIRS grades (ICC = 0.69 and 0.71, respectively), indicating good external construct validity. DM1-Activ is a practical, reliable and valid outcome measure that fulfils all clinimetric requirements. Further evaluation of this scale is needed to provide a nomogram for clinical use. (C) 2010 Elsevier B.V. All rights reserved.
Notes: [Hermans, Mieke C. E.; Faber, Catharina G.; Merkies, Ingemar S. J.] Maastricht Univ, Med Ctr, Dept Neurol, NL-6202 AZ Maastricht, Netherlands. [De Baets, Marc H.] Univ Maastricht, Sch Mental Hlth & Neurosci, Maastricht, Netherlands. [De Baets, Marc H.] Hasselt Univ, Neuroimmunol Grp, Biomed Res Inst, Diepenbeek, Belgium. [de Die-Smulders, Christine E. M.] Maastricht Univ, Med Ctr, Dept Clin Genet, NL-6202 AZ Maastricht, Netherlands. [Merkies, Ingemar S. J.] Spaarne Hosp, Dept Neurol, Hoofddorp, Netherlands. m.hermans@mumc.nl
URI: http://hdl.handle.net/1942/10997
DOI: 10.1016/j.nmd.2010.03.010
ISI #: 000278771300003
ISSN: 0960-8966
Category: A1
Type: Journal Contribution
Validation: ecoom, 2011
Appears in Collections: Research publications

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