Document Server@UHasselt >
Research >
Research publications >

Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/10290

Title: Color Doppler imaging and ocular pulse amplitude in glaucomatous and healthy eyes
Authors: Stalmans, Ingeborg
Harris, Alon
Fieuws, Steffen
Zeyen, Thierry
Vanbellinghen, Veerle
McCranor, Lynne
Siesky, Brent
Issue Date: 2009
Citation: EUROPEAN JOURNAL OF OPHTHALMOLOGY, 19(4). p. 580-587
Abstract: PURPOSE. To determine factors influencing color Doppler imaging (CDI) measurements, to compare retrobulbar flow velocities between patients with glaucoma and healthy controls, and to describe the correlation between CDI and ocular pulse amplitude (OPA). METHODS. Patients with normal tension (n=28) or primary open angle glaucoma (n=19) and healthy controls (n=22) underwent CDI and OPA measurements. Intraocular pressure, corneal thickness, blood pressure, and heart rate were also measured. Spearman correlations were used to explore relations among these variables. A regression model for repeated measures was applied to compare between diagnostic groups the flow velocity indices in the retrobulbar vessels. RESULTS. Retrobulbar diastolic blood flow velocities correlated with diastolic blood pressure and perfusion pressure (range of Spearman rho [rho] coefficients=0.25-0.28; P=0.044-0.013 for the different vessels). Corneal thickness showed a positive correlation with systolic and diastolic flow velocities in the central retinal artery (rho=0.29 and 0.31; P=0.017 and 0.011 for peak systolic and end diastolic velocity, respectively). Systolic and diastolic blood flow velocities were reduced in the retrobulbar vessels of patients with normal tension glaucoma (P=0.0004) as well as primary open angle glaucoma (P=0.003) compared to healthy controls. A correlation was found between OPA and the resistive index in the retrobulbar vessels of the healthy controls (range.=0.42-0.53; P=0.059-0.014). CONCLUSIONS. Retrobulbar blood flow velocities are reduced in patients with primary open angle glaucoma and normal tension glaucoma. Blood pressure and corneal thickness may influence CDI measurements. OPA correlates with the resistive index in CDI. (Eur J Ophthalmol 2009; 19: 580-7)
Notes: [Stalmans, Ingeborg; Zeyen, Thierry; Vanbellinghen, Veerle] Katholieke Univ Leuven Hosp, Dept Ophthalmol, B-3000 Louvain, Belgium. [Harris, Alon; McCranor, Lynne; Siesky, Brent] Indiana Univ, Sch Med, Dept Ophthalmol, Indianapolis, IN 46202 USA. [Fieuws, Steffen] Catholic Univ Louvain, I Biostat, B-3000 Louvain, Belgium. [Fieuws, Steffen] Univ Hasselt, Louvain, Belgium.
URI: http://hdl.handle.net/1942/10290
ISI #: 000271844800010
ISSN: 1120-6721
Category: A1
Type: Journal Contribution
Validation: ecoom, 2010
Appears in Collections: Research publications

Files in This Item:

There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.